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"The use of cat's claw might be beneficial in patients with advanced cancer by improving their quality of life and reducing fatigue. The mechanism of action does not seem to be related to the anti-inflammatory properties of this plant."
de Paula LC, Fonseca F, Perazzo F, et al. J Altern Complement Med. 2015;21(1):22-30. doi:10.1089/acm.2014.0127
"In conclusion, cat's claw is an effective antioxidant, but perhaps more importantly a remarkably potent inhibitor of TNFalpha production. The primary mechanism for cat's claw anti-inflammatory actions appears to be immunomodulation via suppression of TNFalpha synthesis."
Sandoval, M et al. Free radical biology & medicine vol. 29,1 (2000): 71-8. doi:10.1016/s0891-5849(00)00327-0
Commonly prescribed TNFalpha inhibitors:
Conditions treated with TNFalpha inhibitors:
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